SCHEMBL6368607

SCHEMBL6368607

COc1ccc(C=Cc2ccc(N(C)C)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.66
NQO2 P16083 2/20 0.62
RELA Q04206 2/20 0.61
TRPA1 O75762 1/20 0.61
TUBB4A P04350 2/20 0.61
TUBB P07437 2/20 0.61
TUBA3C P0DPH7 2/20 0.61
TUBA1B P68363 2/20 0.61
TUBA4A P68366 2/20 0.61
TUBB4B P68371 2/20 0.61
TUBB3 Q13509 2/20 0.61
TUBB2A Q13885 2/20 0.61
TUBB8 Q3ZCM7 2/20 0.61
TUBA3E Q6PEY2 2/20 0.61
TUBA1A Q71U36 2/20 0.61
TUBA1C Q9BQE3 2/20 0.61
TUBB6 Q9BUF5 2/20 0.61
TUBB2B Q9BVA1 2/20 0.61
TUBB1 Q9H4B7 2/20 0.61
APP P05067 5/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5494948 1.00 MAOB (0.66) MAOBNQO2RELATRPA1TUBB4A
SCHEMBL14467557 0.87 APP (0.68) MAOBNQO2RELATUBB4ATUBB
SCHEMBL55926 0.87 SLC2A1 (0.75) MAOBAPPSLC2A1CYP1A2MAPT
SCHEMBL9915588 0.86 NQO2 (0.69) MAOBNQO2TUBB4ATUBBTUBA3C
Para-Methoxy Cinnamaldehyde SCHEMBL17296511 0.86 MAOB (0.60) MAOBNQO2TUBB4ATUBBTUBA3C
SCHEMBL5490866 0.85 RELA (0.63) NQO2RELATRPA1TUBB4ATUBB
SCHEMBL4403050 0.85 RELA (0.63) NQO2RELATRPA1TUBB4ATUBB
SCHEMBL10031851 0.85 RELA (0.63) MAOBNQO2RELATUBB4ATUBB
SCHEMBL21738407 0.85 RELA (0.63) NQO2RELATRPA1TUBB4ATUBB
SCHEMBL5491168 0.85 RELA (0.63) NQO2RELATRPA1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7491486-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2009-02-17 US disclosed
US-7491486-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2009-02-17 US disclosed
US-20050214222-A1 In vivo imaging of amyloid plaques in glaucoma using intravenous injectable dyes NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR 2005-09-29 US disclosed
US-5196709-A Fluorometry method and apparatus using a semiconductor laser diode as a light source UNIVERSITY OF MARYLAND SYSTEMS (US) 1993-03-23 US disclosed
EP-0242170-A2 Divinyl compounds and chromogenic recording-material prepared by use thereof YAMADA CHEMICAL CO., LTD. (JP) 1987-10-21 EP disclosed