SCHEMBL5494948

SCHEMBL5494948

COc1ccc(/C=C/c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.66
NQO2 P16083 2/20 0.62
RELA Q04206 2/20 0.61
TRPA1 O75762 1/20 0.61
TUBB4A P04350 2/20 0.61
TUBB P07437 2/20 0.61
TUBA3C P0DPH7 2/20 0.61
TUBA1B P68363 2/20 0.61
TUBA4A P68366 2/20 0.61
TUBB4B P68371 2/20 0.61
TUBB3 Q13509 2/20 0.61
TUBB2A Q13885 2/20 0.61
TUBB8 Q3ZCM7 2/20 0.61
TUBA3E Q6PEY2 2/20 0.61
TUBA1A Q71U36 2/20 0.61
TUBA1C Q9BQE3 2/20 0.61
TUBB6 Q9BUF5 2/20 0.61
TUBB2B Q9BVA1 2/20 0.61
TUBB1 Q9H4B7 2/20 0.61
APP P05067 5/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6368607 1.00 MAOB (0.66) MAOBNQO2RELATRPA1TUBB4A
SCHEMBL14467557 0.87 APP (0.68) MAOBNQO2RELATUBB4ATUBB
SCHEMBL55926 0.87 SLC2A1 (0.75) MAOBAPPSLC2A1CYP1A2MAPT
SCHEMBL9915588 0.86 NQO2 (0.69) MAOBNQO2TUBB4ATUBBTUBA3C
Para-Methoxy Cinnamaldehyde SCHEMBL17296511 0.86 MAOB (0.60) MAOBNQO2TUBB4ATUBBTUBA3C
SCHEMBL5490866 0.85 RELA (0.63) NQO2RELATRPA1TUBB4ATUBB
SCHEMBL4403050 0.85 RELA (0.63) NQO2RELATRPA1TUBB4ATUBB
SCHEMBL10031851 0.85 RELA (0.63) MAOBNQO2RELATUBB4ATUBB
SCHEMBL21738407 0.85 RELA (0.63) NQO2RELATRPA1TUBB4ATUBB
SCHEMBL5491168 0.85 RELA (0.63) NQO2RELATRPA1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3951890-B1 N-TYPE SEMICONDUCTOR ELEMENT, METHOD FOR PRODUCING N-TYPE SEMICONDUCTOR ELEMENT, WIRELESS COMMUNICATION DEVICE AND PRODUCT TAG TORAY INDUSTRIES (JP) 2025-01-01 EP disclosed
US-12029107-B2 n-type semiconductor element, method for producing n-type semiconductor element, wireless communication device, and product tag TORAY INDUSTRIES, INC. (JP) 2024-07-02 US disclosed
US-20220158098-A1 n-TYPE SEMICONDUCTOR ELEMENT, METHOD FOR PRODUCING n-TYPE SEMICONDUCTOR ELEMENT, WIRELESS COMMUNICATION DEVICE, AND PRODUCT TAG TORAY INDUSTRIES, INC. (JP) 2022-05-19 US disclosed
CN-113646900-B n-type semiconductor element, method for manufacturing the same, wireless communication device, and merchandise tag 东丽株式会社 2022-05-13 CN disclosed
EP-3951890-A1 N-TYPE SEMICONDUCTOR ELEMENT, METHOD FOR PRODUCING N-TYPE SEMICONDUCTOR ELEMENT, WIRELESS COMMUNICATION DEVICE AND PRODUCT TAG TORAY INDUSTRIES, INC. (JP) 2022-02-09 EP disclosed
US-9925153-B2 Therapeutic agents for skin diseases and conditions STC.UNM (US) 2018-03-27 US disclosed
US-20160287531-A1 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS STC.UNM 2016-10-06 US disclosed
US-8980954-B2 Substituted cis- and trans-stilbenes as therapeutic agents STC.UNM (US) 2015-03-17 US disclosed
US-20130178536-A1 SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS STC.UNM (US) 2013-07-11 US disclosed
US-7759502-B2 Useful for inhibiting the aggregation of amyloid protein to form amyloid deposit THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2010-07-20 US disclosed
US-20080108840-A1 Stilbene Derivatives And Their Use For Binding And Imaging Amyloid Plaques TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2008-05-08 US disclosed
US-7297820-B2 Stilbene derivatives and their use for binding and imaging amyloid plaques TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-11-20 US disclosed
US-7297820-B2 Stilbene derivatives and their use for binding and imaging amyloid plaques TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-11-20 US disclosed
US-20070249647-A1 Substituted CIS- and trans-stilbenes as therapeutic agents REGENTS OF THE UNIVERSITY OF NEW MEXICO 2007-10-25 US disclosed
US-7250525-B2 Stilbene derivatives and their use for binding and imaging amyloid plaques THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-07-31 US disclosed
US-7250525-B2 Stilbene derivatives and their use for binding and imaging amyloid plaques THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-07-31 US disclosed
US-20050214222-A1 In vivo imaging of amyloid plaques in glaucoma using intravenous injectable dyes NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR 2005-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160287531-A1 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS CUTA, TSLP, ELANE MAOB 961/4885NQO2 344/4885RELA 29/4885
US-20080108840-A1 Stilbene Derivatives And Their Use For Binding And Imaging Amyloid Plaques APP, APBA1, PSEN1 MAOB 748/4885NQO2 2826/4885RELA 2968/4885
US-20070249647-A1 Substituted CIS- and trans-stilbenes as therapeutic agents TGFB1, VHL, TMSB10 MAOB 1359/4885NQO2 869/4885RELA 12/4885
US-20130178536-A1 SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS PSEN1, TERT, PSEN2 MAOB 933/4885NQO2 657/4885RELA 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.