SCHEMBL670670

SCHEMBL670670

Oc1ccc2ccc3ccc(O)cc3c2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.52
MCL1 Q07820 1/20 0.52
LMNA P02545 3/20 0.48
ESR1 P03372 4/20 0.48
ESR2 Q92731 4/20 0.48
CYP3A4 P08684 4/20 0.48
ALOX15 P16050 3/20 0.48
HSD17B10 Q99714 3/20 0.48
HIF1A Q16665 2/20 0.48
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CDK4 P11802 1/20 0.47
CCND1 P24385 1/20 0.47
F12 P00748 1/20 0.46
RAD52 P43351 1/20 0.46
TYR P14679 2/20 0.44
ABL1 P00519 1/20 0.44
ABCB1 P08183 1/20 0.44
BCR P11274 1/20 0.44
KDM4E B2RXH2 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6369167 0.89 CYP1A2 (0.50) CYP1A2MCL1LMNAESR1ESR2
SCHEMBL29941879 0.87 ALDH1A1 (0.64) CYP1A2MCL1ESR1ESR2CYP3A4
SCHEMBL2463822 0.87 ALDH1A1 (0.64) CYP1A2MCL1ESR1ESR2CYP3A4
Methane SCHEMBL28023590 0.84 ALDH1A1 (0.61) CYP1A2MCL1ESR1ESR2CYP3A4
SCHEMBL1758779 0.84 ALOX15 (0.48) CYP1A2MCL1LMNAESR1ESR2
SCHEMBL31001170 0.83 CYP1A2 (0.62) CYP1A2MCL1ESR1ESR2CYP3A4
SCHEMBL26132517 0.83 HPRT1 (0.64) CYP1A2MCL1CYP3A4HSD17B10HIF1A
SCHEMBL14809442 0.83 HPRT1 (0.64) CYP1A2MCL1CYP3A4HSD17B10HIF1A
SCHEMBL29848183 0.81 ESR1 (0.44) CYP1A2MCL1LMNAESR1ESR2
SCHEMBL12251173 0.81 ESR1 (0.44) CYP1A2MCL1LMNAESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109010916-B Moldable formulations containing oxysterol in acellular tissue matrices 华沙整形外科股份有限公司 2022-03-04 CN claimed
CN-108079374-B Freeze-dried moldable implant containing oxysterol 华沙整形外科股份有限公司 2022-03-04 CN claimed
CN-108495660-B Electron beam irradiated osteoinductive bone implant 华沙整形外科股份有限公司 2022-03-22 CN disclosed
CN-108079374-B Freeze-dried moldable implant containing oxysterol 华沙整形外科股份有限公司 2022-03-04 CN disclosed
CN-109010916-B Moldable formulations containing oxysterol in acellular tissue matrices 华沙整形外科股份有限公司 2022-03-04 CN disclosed
CN-104903363-B Monomer, liquid-crystal composition, the manufacture method of liquid crystal display device and liquid crystal display device 夏普株式会社 2018-05-04 CN disclosed
CN-107109056-A Resin film formation composition and resin film 日产化学工业株式会社 2017-08-29 CN disclosed
CN-106873248-A Liquid crystal display panel and liquid crystal display device 夏普株式会社 2017-06-20 CN disclosed
US-9676907-B2 Methods and systems of graft polymerization on a functionalized substrate ASPEN RESEARCH CORPORATION (US) 2017-06-13 US disclosed
CN-106662767-A Liquid-crystal display 夏普株式会社 2017-05-10 CN disclosed
CN-103765305-B Liquid crystal display panel and liquid crystal display device 夏普株式会社 2017-04-12 CN disclosed
WO-2012024584-A2 OXYSTEROL COMPOUNDS FATE THERAPEUTICS, INC. (US) 2012-02-23 WO disclosed
EP-1122746-B1 Composition for film formation and insulating film JSR CORP (JP) 2004-09-22 EP disclosed
US-6468589-B2 A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING JSR CORPORATION (JP) 2002-10-22 US disclosed
US-20010012870-A1 Composition for film formation and insulating film JSR CORPORATION (JP) 2001-08-09 US disclosed
EP-1122746-A1 Composition for film formation and insulating film JSR Corporation (JP) 2001-08-08 EP disclosed
EP-0320227-B1 Method of preventing polymer-scale formation SHINETSU CHEMICAL CO (JP) 1994-09-07 EP disclosed
CN-1023324-C Method of preventing polymer-scale formation SHINETSU CHEMICAL CO (JP) 1993-12-29 CN disclosed
US-4933399-A COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-06-12 US disclosed
CN-1035118-A A kind of method that forms polymer-scale that stops SHINETSU CHEMICAL CO (JP) 1989-08-30 CN disclosed