Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554482 | 0.96 | ALDH1A1 (0.58) | ALDH1A1POLBHPGDHTTHRH3 | |
| SCHEMBL63892 | 0.89 | ALDH1A1 (0.63) | ALDH1A1POLBHPGDHTTHRH3 | |
| SCHEMBL6135228 | 0.89 | ALDH1A1 (0.67) | ALDH1A1POLBHPGDHTTHRH3 | |
| SCHEMBL6134915 | 0.88 | ALDH1A1 (0.65) | ALDH1A1POLBHPGDHTTNPC1 | |
| SCHEMBL64407 | 0.86 | ALDH1A1 (0.58) | ALDH1A1POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL64179 | 0.86 | HRH3 (0.50) | ALDH1A1POLBHRH3NPC1TDP1 | |
| SCHEMBL63474 | 0.86 | ALDH1A1 (0.59) | ALDH1A1POLBHPGDHTTMAPT | |
| SCHEMBL6369256 | 0.84 | ALDH1A1 (0.61) | ALDH1A1POLBHPGDHTTHRH3 | |
| SCHEMBL18795043 | 0.83 | BTK (0.57) | ALDH1A1POLBHRH3NPC1SMN1; SMN2 | |
| SCHEMBL64181 | 0.82 | ALDH1A1 (0.49) | ALDH1A1POLBHRH3MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014685-A1 | New compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014685-A1 | New compound | MAN2B1, MAN2A1, MANBA | ALDH1A1 4110/4885POLB 1247/4885HPGD 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.