Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 16/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | APOB | P04114 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727646 | 0.94 | MTTP (0.46) | MTTPPPARGPPARDPPARANR1H4 | |
| SCHEMBL6368399 | 0.93 | MTTP (0.39) | MTTPPPARGPPARDPPARANR1H4 | |
| SCHEMBL3730595 | 0.93 | MTTP (0.45) | MTTPPPARGPPARDPPARANR1H4 | |
| SCHEMBL6368735 | 0.93 | ALDH1A1 (0.38) | MTTPGAA | |
| SCHEMBL3723761 | 0.92 | MTTP (0.45) | MTTPPPARGPPARDPPARANR1H4 | |
| SCHEMBL3727471 | 0.91 | MTTP (0.46) | MTTPAPOB | |
| SCHEMBL3726100 | 0.91 | MTTP (0.52) | MTTPGAANR1H4APOB | |
| SCHEMBL3725208 | 0.91 | MTTP (0.48) | MTTPGAAAPOB | |
| SCHEMBL3723744 | 0.91 | MTTP (0.46) | MTTPPPARGPPARDPPARANR1H4 | |
| SCHEMBL3727216 | 0.91 | MTTP (0.46) | MTTPPPARGPPARDPPARANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075367-A1 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | US | claimed |
| EP-2397129-A1 | Agent for the treatment or prevention of diabetes, obesity or arteriosclerosis | Japan Tobacco, Inc. (JP) | 2011-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075367-A1 | Ester compound and medicinal use thereof | LIPC, CES1, MTTP | MTTP 3/4885GAA 2055/4885PPARG 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.