Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethyl Oleate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | DGKA | P23743 | 1/20 | 0.66 |
| ▸ | FAAH | O00519 | 2/20 | 0.66 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.62 |
| ▸ | PRKCA | P17252 | 1/20 | 0.62 |
| ▸ | MGLL | Q99685 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | TERT | O14746 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Oleate SCHEMBL6369777 | 1.00 | ALOX15 (0.69) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| Ethyl Oleate SCHEMBL1896892 | 0.96 | HSD17B10 (0.73) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL3847096 | 0.96 | HSD17B10 (0.73) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL7557819 | 0.96 | HSD17B10 (0.73) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL588561 | 0.96 | HSD17B10 (0.73) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL25490302 | 0.96 | HSD17B10 (0.73) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL588560 | 0.96 | HSD17B10 (0.73) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL12842074 | 0.96 | HSD17B10 (0.73) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| Ethyl Oleate SCHEMBL2798 | 0.96 | HSD17B10 (0.73) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL546545 | 0.96 | HSD17B10 (0.73) | ALOX15HSD17B10ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11364299-B2 | Non-addictive analgesic sustained-release drug delivery system and preparation method thereof | LIPONT PHARMACEUTICALS INC. (CA) | 2022-06-21 | — | — | US | disclosed |
| EP-2949316-B1 | NON-ADDICTIVE ANALGESIC SUSTAINED-RELEASE DRUG DELIVERY SYSTEM AND PREPARATION METHOD THEREOF | XIAN LIBANG PHARMACEUTICAL CO LTD (CN) | 2020-07-01 | — | — | EP | disclosed |
| US-20150359891-A1 | NON-ADDICTIVE ANALGESIC SUSTAINED-RELEASE DRUG DELIVERY SYSTEM AND PREPARATION METHOD THEREOF | LIPONT PHARMACEUTICALS INC. (CA) | 2015-12-17 | — | — | US | disclosed |
| EP-2949316-A1 | NON-ADDICTIVE ANALGESIC SUSTAINED-RELEASE DRUG DELIVERY SYSTEM AND PREPARATION METHOD THEREOF | Lipont Pharmaceuticals Inc. (CA) | 2015-12-02 | — | — | EP | disclosed |
| CN-103142458-B | Without prescription and the preparation method of additive analgesia sustained release drug delivery systems | LAIPUDE PHARMACEUTICAL CO., LTD. (CA) | 2015-09-09 | — | — | CN | disclosed |
| CN-103142458-A | Component and preparation method of non-addition analgesia slow release medicine delivering system | LAIPUDE PHARMACEUTICAL CO LTD | 2013-06-12 | — | — | CN | disclosed |
| US-6960563-B2 | Spontaneous emulsions containing cyclosporine | MORTON GROVE PHARMACEUTICALS, INC. (US) | 2005-11-01 | — | — | US | disclosed |
| WO-2003017947-A3 | SPONTANEOUS EMULSIONS CONTAINING CYCLOSPORINE | MORTON GROVE PHARMACEUTICALS I (US) | 2004-01-29 | — | — | WO | disclosed |
| US-20030049280-A1 | Spontaneous emulsions containing cyclosporine | WOCKHARDT EU OPERATIONS (SWISS) AG (CH) | 2003-03-13 | — | — | US | disclosed |
| WO-2003017947-A2 | SPONTANEOUS EMULSIONS CONTAINING CYCLOSPORINE | MORTON GROVE PHARMACEUTICALS, INC. (US) | 2003-03-06 | — | — | WO | disclosed |
| US-4956286-A | ESTERIFICATION OF FATTY ACIDS OR GLYCERIDES WITH ALCOHOLS BY AN ENZYME CATALYZED REACTION | UNILEVER PATENT HOLDINGS B.V. (NL) | 1990-09-11 | — | — | US | disclosed |