Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | LTK | P29376 | 1/20 | 0.60 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985609 | 0.83 | KAT2B (0.57) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8555813 | 0.83 | MAPT (0.46) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8039525 | 0.81 | HCAR3 (0.55) | IDO1MAPTKMT2ANPSR1NSD2 | |
| SCHEMBL10644777 | 0.78 | MAPT (0.50) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL11143939 | 0.77 | MAPT (0.49) | IDO1MAPTKMT2ANPSR1NSD2 | |
| Hydrochloric Acid SCHEMBL31741335 | 0.77 | MAPT (0.65) | IDO1MAPTKMT2AALDH1A1CTSB | |
| SCHEMBL10848831 | 0.77 | NQO2 (0.59) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL1594633 | 0.77 | MAPT (0.56) | MAPTNPSR1ALDH1A1LMNAPOLB | |
| SCHEMBL5394907 | 0.76 | MAPT (0.56) | MAPTKMT2ANPSR1NSD2ALDH1A1 | |
| SCHEMBL12515299 | 0.76 | KAT2B (0.56) | MAPTKMT2ANPSR1NSD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846953-B1 | Aromatic amides | WARNER LAMBERT COMPANY (US) | 2005-01-25 | — | — | US | claimed |
| EP-1178953-B1 | AROMATIC AMIDES | WARNER LAMBERT CO (US) | 2003-12-03 | — | — | EP | claimed |
| JP-2002544186-A | — | — | 2002-12-24 | — | — | JP | claimed |
| EP-1178953-A1 | AROMATIC AMIDES | WARNER-LAMBERT COMPANY (US) | 2002-02-13 | — | — | EP | claimed |
| WO-2000068184-A1 | AROMATIC AMIDES | WARNER-LAMBERT COMPANY (US) | 2000-11-16 | — | — | WO | claimed |