Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370241 | 0.83 | CHEK1 (0.60) | MAPTKMT2ANPSR1NSD2ALDH1A1 | |
| SCHEMBL11143939 | 0.79 | MAPT (0.49) | MAPTKMT2ANPSR1NSD2ALDH1A1 | |
| SCHEMBL8039525 | 0.77 | HCAR3 (0.55) | MAPTKMT2ANPSR1NSD2ALDH1A1 | |
| SCHEMBL8886382 | 0.76 | MAPT (0.63) | MAPTKMT2ANPSR1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL31741335 | 0.76 | MAPT (0.65) | MAPTKMT2AALDH1A1CTSBTDP1 | |
| SCHEMBL11137210 | 0.76 | MAPT (0.52) | MAPTKMT2ANPSR1NSD2ALDH1A1 | |
| SCHEMBL5394907 | 0.75 | MAPT (0.56) | MAPTKMT2ANPSR1NSD2ALDH1A1 | |
| SCHEMBL3814746 | 0.75 | TDP1 (0.55) | MAPTKMT2AALDH1A1MEN1CTSB | |
| SCHEMBL8885076 | 0.73 | MAPT (0.50) | MAPTKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL20259977 | 0.72 | HTR6 (0.48) | MAPTKMT2ANPSR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |