Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 5/20 | 0.34 |
| ▸ | LITAF | Q99732 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RBP1 | P09455 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6377172 | 0.91 | KCNH2 (0.39) | KCNH2TNFLITAFCYP3A4PIK3CA | |
| SCHEMBL6376752 | 0.90 | KCNH2 (0.36) | KCNH2TNFLITAFCYP3A4 | |
| SCHEMBL6370842 | 0.87 | TNF (0.30) | TNFLITAF | |
| SCHEMBL6371393 | 0.83 | ALDH1A1 (0.36) | KCNH2TNFLITAFCYP3A4 | |
| SCHEMBL6371670 | 0.83 | KCNH2 (0.43) | KCNH2TNFLITAFCYP3A4 | |
| SCHEMBL6371181 | 0.83 | KCNH2 (0.35) | KCNH2TNFLITAFCYP3A4 | |
| SCHEMBL6377186 | 0.82 | KCNH2 (0.45) | KCNH2TNFLITAFCYP3A4 | |
| SCHEMBL6371152 | 0.82 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL6372031 | 0.81 | KCNH2 (0.37) | KCNH2CYP3A4RBP1PIK3CAMTOR | |
| SCHEMBL6370135 | 0.81 | KCNH2 (0.45) | KCNH2TNFLITAFCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096278-A1 | Antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-05 | — | — | US | claimed |
| WO-2005026145-A2 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | claimed |
| US-20050096278-A1 | Antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096278-A1 | Antibacterial agents | MRPL21, FBL, SDHA | KCNH2 2194/4885TNF 2496/4885LITAF 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.