Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370759 | 0.90 | KCNH2 (0.44) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL6377219 | 0.89 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL1383899 | 0.88 | KCNH2 (0.54) | KCNH2POLB | |
| Hydrochloric Acid SCHEMBL4500466 | 0.87 | KCNH2 (0.53) | KCNH2POLB | |
| SCHEMBL6501955 | 0.86 | KCNH2 (0.51) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL6370029 | 0.85 | KCNH2 (0.47) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL1383222 | 0.84 | KCNH2 (0.42) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL6370746 | 0.84 | KCNH2 (0.43) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL5463875 | 0.84 | KCNH2 (0.49) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL6371424 | 0.84 | KCNH2 (0.42) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096278-A1 | Antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-05 | — | — | US | claimed |
| WO-2005026145-A2 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | claimed |
| US-20050096278-A1 | Antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-05 | — | — | US | disclosed |
| WO-2005026145-A2 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096278-A1 | Antibacterial agents | MRPL21, FBL, SDHA | KCNH2 2194/4885POLB 519/4885KDM4E 3873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.