SCHEMBL6370889

SCHEMBL6370889

O=S(=O)(O)c1ccc2[nH][c]nc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.40
ALDH1A1 P00352 6/20 0.37
HSD17B10 Q99714 4/20 0.37
TDP1 Q9NUW8 3/20 0.36
HPGD P15428 2/20 0.36
THRB P10828 2/20 0.36
BLM P54132 2/20 0.36
F2 P00734 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
MAPT P10636 1/20 0.36
PTGS1 P23219 1/20 0.36
KDR P35968 1/20 0.36
WRN Q14191 1/20 0.36
ENPP2 Q13822 1/20 0.36
LMNA P02545 1/20 0.35
PTPN11 Q06124 3/20 0.35
TSHR P16473 3/20 0.34
NT5E P21589 1/20 0.34
KDM4E B2RXH2 2/20 0.34
PARP1 P09874 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3591821 0.83 NPBWR1 (0.40) ENPP2SMN1; SMN2
SCHEMBL2027807 0.80
SCHEMBL1156233 0.70 HDAC6 (0.41) HDAC6ALDH1A1HSD17B10TDP1HPGD
SCHEMBL828238 0.70 HDAC6 (0.59) HDAC6ALDH1A1HSD17B10TDP1HPGD
SCHEMBL571363 0.70 PRKCI (0.42) HDAC6ALDH1A1HSD17B10TDP1HPGD
SCHEMBL10770660 0.70 LMNA (0.45) HDAC6ALDH1A1HSD17B10MAPTENPP2
SCHEMBL9453804 0.69 HDAC6 (0.40) HDAC6ALDH1A1HSD17B10TDP1HPGD
SCHEMBL11227448 0.69 NPBWR1 (0.47)
Ammonia Solution, Strong SCHEMBL6052135 0.69 HDAC6 (0.40) HDAC6ALDH1A1HSD17B10TDP1HPGD
SCHEMBL8423877 0.69 HDAC6 (0.40) HDAC6ALDH1A1HSD17B10TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107690329-B Pituitous silicone emulsions 美国陶氏有机硅公司 2021-10-08 CN disclosed
CN-106795373-B Silicone elastomer composition 美国陶氏有机硅公司 2020-06-05 CN disclosed
CN-107207740-B Method for preparing functionalized particles 美国陶氏有机硅公司 2020-03-17 CN disclosed
CN-106536634-B Viscous silicone fluids 美国陶氏有机硅公司 2020-03-17 CN disclosed
US-6893810-B1 Silver halide color photographic light-sensitive material for movie FUJI PHOTO FILM CO., LTD. (JP) 2005-05-17 US disclosed
US-6043242-A TREATING A MAMMAL AFFLICTED WITH A DISEASE BASED ON HELICOBACTER BACTERIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-03-28 US disclosed
EP-0946559-A2 IMIDAZOPYRIDAZINES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1999-10-06 EP disclosed
WO-1998028299-A2 IMIDAZOPYRIDAZINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1998-07-02 WO disclosed
EP-0530511-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1998-06-03 EP disclosed
US-5422238-A Contains methine compound FUJI PHOTO FILM CO., LTD. (JP) 1995-06-06 US disclosed
US-5290668-A Photographic films with waterproof layers on supports for color photography FUJI PHOTO FILM CO., LTD. (JP) 1994-03-01 US disclosed
US-5252447-A Sharpness, whiteness, storage stability FUJI PHOTO FILM CO., LTD. (JP) 1993-10-12 US disclosed
EP-0530511-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-03-10 EP disclosed
US-5151345-A Photographic film with a reflective support coated wtih a waterproof resin layer and titanium oxide FUJI PHOTO FILM CO., LTD. (JP) 1992-09-29 US disclosed
US-5013636-A Magenta coupler and water soluble dye, films and paper FUJI PHOTO FILM CO., LTD. (JP) 1991-05-07 US disclosed
EP-0360289-A2 Positive working silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-03-28 EP disclosed