Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916413 | 0.99 | EPHX2 (0.36) | EPHX2ADAMTS4MMP8ADAMTS5TAAR1 | |
| SCHEMBL917465 | 0.90 | ADAMTS4 (0.38) | EPHX2ADAMTS4MMP8ADAMTS5FAAH | |
| SCHEMBL636929 | 0.90 | ADAMTS4 (0.38) | EPHX2ADAMTS4MMP8ADAMTS5TAAR1 | |
| SCHEMBL637343 | 0.89 | ADAMTS4 (0.37) | EPHX2ADAMTS4MMP8ADAMTS5FAAH | |
| SCHEMBL2231584 | 0.81 | TAAR1 (0.41) | TAAR1KMT2ATDP1LMNALIPE | |
| SCHEMBL640972 | 0.80 | TAAR1 (0.41) | TAAR1KMT2ATDP1LMNALIPE | |
| SCHEMBL640478 | 0.79 | KMT2A (0.36) | EPHX2ADAMTS4MMP8ADAMTS5TAAR1 | |
| SCHEMBL2230591 | 0.79 | KMT2A (0.42) | TAAR1KMT2ATDP1LMNALIPE | |
| SCHEMBL916227 | 0.78 | EPHX2 (0.36) | EPHX2ADAMTS4MMP8ADAMTS5TAAR1 | |
| SCHEMBL916877 | 0.78 | KMT2A (0.41) | TAAR1KMT2ATDP1LMNALIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660440-B1 | ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE | XENOPORT INC (US) | 2012-02-22 | — | — | EP | disclosed |