SCHEMBL637177

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16492331	0.79	TDP1 (0.53)	TDP1ALDH1A1GLATSHRTP53
	SCHEMBL776297	0.76	TSHR (0.38)	TDP1ALDH1A1TSHRTP53CYP3A4
	Aminodiphenylmethane SCHEMBL27998810	0.76	TDP1 (0.50)	TDP1ALDH1A1GLATSHRTP53
	Styrene SCHEMBL1355033	0.76	ALDH1A1 (0.50)	TDP1ALDH1A1GLATSHRTP53
	SCHEMBL5704259	0.76	TDP1 (0.50)	TDP1ALDH1A1GLATSHRTP53
	SCHEMBL28334094	0.75	ALDH1A1 (0.42)	TDP1ALDH1A1GLATSHRTP53
	SCHEMBL194266	0.75	TDP1 (0.46)	TDP1ALDH1A1GLATSHRTP53
	Styrene SCHEMBL28133285	0.74	TDP1 (0.49)	TDP1ALDH1A1GLATSHRTP53
	SCHEMBL27994199	0.74	TDP1 (0.49)	TDP1ALDH1A1GLATSHRTP53
	Hydrochloric Acid SCHEMBL11163950	0.74	CYP2C19 (0.36)	TDP1ALDH1A1TSHRTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.