Styrene

Styrene

SCHEMBL28133285

C.C(OCC1CO1)C1CO1.C=Cc1ccccc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.49
ALDH1A1 P00352 4/20 0.48
TSHR P16473 4/20 0.48
GLA P06280 1/20 0.41
MGLL Q99685 3/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1355033 0.98 ALDH1A1 (0.50) TDP1ALDH1A1TSHRGLAMGLL
Styrene SCHEMBL28699410 0.92 TDP1 (0.47) TDP1ALDH1A1TSHRGLAMGLL
Styrene SCHEMBL29150889 0.91 TDP1 (0.44) TDP1ALDH1A1TSHRGLAMGLL
Styrene SCHEMBL28095487 0.89 ALDH1A1 (0.66) TDP1ALDH1A1TSHRGLAMGLL
SCHEMBL10824732 0.89 MGLL (0.53) TDP1ALDH1A1TSHRGLAMGLL
Styrene SCHEMBL28934083 0.89 TDP1 (0.45) TDP1ALDH1A1TSHRGLAMGLL
Styrene SCHEMBL28076081 0.85 TDP1 (0.47) TDP1ALDH1A1TSHRGLAMGLL
Styrene SCHEMBL27589205 0.85 TDP1 (0.47) TDP1ALDH1A1TSHRGLAMGLL
SCHEMBL17761547 0.82 ALDH1A1 (0.50) TDP1ALDH1A1TSHRGLAMGLL
Styrene SCHEMBL27260179 0.82 TDP1 (0.45) TDP1ALDH1A1TSHRGLAMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795228-B Solidification compound 住友化学株式会社 2019-08-30 CN disclosed
CN-106795228-A Solidification compound 住友化学株式会社 2017-05-31 CN disclosed
CN-106604937-A Curable composition 住友化学株式会社 2017-04-26 CN disclosed