Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1251937 | 0.99 | PARP1 (0.55) | PARP1NPC1RAB9A | |
| SCHEMBL6374708 | 0.99 | PARP1 (0.54) | PARP1 | |
| Bromide SCHEMBL1251641 | 0.98 | PARP1 (0.53) | PARP1 | |
| SCHEMBL1252619 | 0.96 | PARP1 (0.54) | PARP1 | |
| SCHEMBL1251301 | 0.95 | PARP1 (0.54) | PARP1 | |
| SCHEMBL1252947 | 0.93 | PARP1 (0.54) | PARP1 | |
| SCHEMBL1252555 | 0.93 | PARP1 (0.54) | PARP1 | |
| Bromide SCHEMBL1249847 | 0.92 | PARP1 (0.53) | PARP1 | |
| SCHEMBL6378632 | 0.92 | PARP1 (0.52) | PARP1 | |
| SCHEMBL6379728 | 0.92 | PARP1 (0.52) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050085476-A1 | Fused pyridazine derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085476-A1 | Fused pyridazine derivative compounds and drugs containing the compounds as the active ingredient | MUSK, RNASE1, DPYD | PARP1 4/4885NPC1 4197/4885RAB9A 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.