SCHEMBL637358

SCHEMBL637358

Cc1ccccc1-n1c(N)nc2[nH]cnc2c1=O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR1 Q9BXC0 4/20 0.48
PDE4D Q08499 4/20 0.45
PDE4A P27815 3/20 0.45
PDE4B Q07343 3/20 0.45
PDE4C Q08493 3/20 0.45
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 4/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 1/20 0.40
EPHB4 P54760 2/20 0.39
PARP1 P09874 1/20 0.38
RAB9A P51151 1/20 0.38
PIK3CD O00329 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
PIK3R1 P27986 1/20 0.36
PIK3CB P42338 1/20 0.36
PIK3CG P48736 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21768327 0.85 HCAR1 (0.49) HCAR1ALDH1A1PARP1PIK3CG
SCHEMBL1286952 0.83 HCAR1 (0.49) HCAR1PDE4DPDE4APDE4BPDE4C
SCHEMBL1286942 0.81 PDE4A (0.45) HCAR1PDE4DPDE4APDE4BPDE4C
SCHEMBL8039252 0.80 PARP1 (0.34) HCAR1PARP1
SCHEMBL637361 0.79 PDE4D (0.50) HCAR1PDE4DPDE4APDE4BPDE4C
SCHEMBL1286937 0.77 GSR (0.37) HCAR1PDE4DPDE4APDE4BPDE4C
SCHEMBL1286921 0.77 GSR (0.36) HCAR1PDE4DPDE4APDE4BPDE4C
SCHEMBL6952177 0.76 MEN1 (0.41) PDE4DPDE4APDE4BPDE4CKMT2A
SCHEMBL1553505 0.76 HCAR1 (0.48) HCAR1PDE4DKMT2AALDH1A1LMNA
SCHEMBL1286934 0.75 MAPK9 (0.38) ALDH1A1LMNANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118203522-A Sugar-resistant, oxidation-resistant and aging-resistant compound and preparation method and application thereof 上海肤徕生物高科技有限公司 2024-06-18 CN claimed
CN-118203522-A Sugar-resistant, oxidation-resistant and aging-resistant compound and preparation method and application thereof 上海肤徕生物高科技有限公司 2024-06-18 CN disclosed
EP-2990438-B1 NITRILE RUBBER COMPOSITION, CROSSLINKABLE RUBBER COMPOSITION, AND CROSSLINKED RUBBER PRODUCT ZEON CORP (JP) 2020-04-01 EP disclosed
US-20160090464-A1 NITRILE RUBBER COMPOSITION, CROSS-LINKABLE RUBBER COMPOSITION, AND CROSS-LINKED RUBBER ZEON CORPORATION (JP) 2016-03-31 US disclosed
EP-2990438-A1 NITRILE RUBBER COMPOSITION, CROSSLINKABLE RUBBER COMPOSITION, AND CROSSLINKED RUBBER PRODUCT Zeon Corporation (JP) 2016-03-02 EP disclosed
US-8642718-B2 Curable composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-02-04 US disclosed
EP-1882713-B1 CURABLE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2013-07-03 EP disclosed
EP-2546308-A2 Curable composition KANEKA CORPORATION (JP) 2013-01-16 EP disclosed
EP-2546307-A2 Curable composition KANEKA CORPORATION (JP) 2013-01-16 EP disclosed
EP-1775315-B1 POLYMERIZABLE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2012-02-22 EP disclosed
US-20040122201-A1 polysulfides; improved impact resistance MITSUBISHI GAS CHEMICAL COMPANY (JP) 2004-06-24 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed
EP-1413597-A1 Thermally expandable material, method for producing the same and soundproof sheet for automobiles NICHIAS CORPORATION (JP) 2004-04-28 EP disclosed
EP-1398317-A1 ALICYCLIC COMPOUND FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-03-17 EP disclosed
EP-1326095-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-07-09 EP disclosed
EP-1319966-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-06-18 EP disclosed
US-4877817-A BLEND WITH A MERCAPTOTRIAZINE COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-10-31 US disclosed
EP-0087790-B1 EPOXY RESIN COMPOSITION Hitachi, Ltd. (JP) 1986-11-05 EP disclosed
US-4460718-A EPOXY-MODIFIED 1-O-TOLYLBIGUANIDE HITACHI, LTD. (JP) 1984-07-17 US disclosed
EP-0087790-A1 Epoxy resin composition Hitachi, Ltd. (JP) 1983-09-07 EP disclosed