Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 12/20 | 0.50 |
| ▸ | NPC1 | O15118 | 10/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809685 | 0.79 | RAB9A (0.50) | MAPTRAB9ANPC1POLBHPGD | |
| SCHEMBL9080024 | 0.79 | RAB9A (0.50) | MAPTRAB9ANPC1POLBHPGD | |
| SCHEMBL9345674 | 0.79 | MAPT (0.50) | MAPTRAB9ANPC1POLBHPGD | |
| SCHEMBL9345666 | 0.79 | MAPT (0.50) | MAPTRAB9ANPC1POLBHPGD | |
| SCHEMBL11225467 | 0.77 | MAPT (0.62) | MAPTRAB9ANPC1POLBHPGD | |
| SCHEMBL9463368 | 0.76 | MAPT (0.47) | MAPTRAB9ANPC1POLBHPGD | |
| SCHEMBL5630056 | 0.75 | MAPT (0.64) | MAPTRAB9ANPC1POLBHPGD | |
| SCHEMBL1691061 | 0.75 | MAPT (0.68) | MAPTRAB9ANPC1POLBHPGD | |
| SCHEMBL10816647 | 0.75 | RAB9A (0.71) | MAPTRAB9ANPC1POLBHPGD | |
| SCHEMBL11225869 | 0.74 | MAPT (0.58) | MAPTRAB9ANPC1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005072731-A1 | 3-PHENYL-N- ((1, 3, 4) THIADIAZOL-2-YL) -ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ESTROGEN-RELATED RECEPTORS FOR THE TREATMENT OF E.G. CANCER, RHEUMATOID ARTHRITIS OR NEUROLOGICAL DISORDERS | X-CEPTOR THERAPEUTICS, INC. (US) | 2005-08-11 | — | — | WO | disclosed |