Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657490 | 0.89 | HSP90AA1 (0.50) | GRIN2BHSP90AA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8480845 | 0.84 | GRIN2B (0.57) | GRIN2BGRIN2AALDH1A1KMT2AMEN1 | |
| SCHEMBL8988234 | 0.83 | HSP90AA1 (0.46) | GRIN2BHSP90AA1ALDH1A1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8655604 | 0.82 | HSP90AA1 (0.45) | GRIN2BHSP90AA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11657276 | 0.80 | POLB (0.46) | GRIN2BHSP90AA1GRIN2APOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7324295 | 0.77 | GRIN2B (0.63) | GRIN2BGRIN2AALDH1A1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7331599 | 0.77 | GRIN2B (0.54) | GRIN2BGRIN2AALDH1A1KMT2AMEN1 | |
| SCHEMBL8481972 | 0.76 | GRIN2B (0.59) | GRIN2BGRIN2AALDH1A1SMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL7320117 | 0.75 | GRIN2B (0.52) | GRIN2BGRIN2ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL15362563 | 0.74 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2KMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005072731-A1 | 3-PHENYL-N- ((1, 3, 4) THIADIAZOL-2-YL) -ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ESTROGEN-RELATED RECEPTORS FOR THE TREATMENT OF E.G. CANCER, RHEUMATOID ARTHRITIS OR NEUROLOGICAL DISORDERS | X-CEPTOR THERAPEUTICS, INC. (US) | 2005-08-11 | — | — | WO | disclosed |
| WO-2005072731-A1 | 3-PHENYL-N- ((1, 3, 4) THIADIAZOL-2-YL) -ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ESTROGEN-RELATED RECEPTORS FOR THE TREATMENT OF E.G. CANCER, RHEUMATOID ARTHRITIS OR NEUROLOGICAL DISORDERS | X-CEPTOR THERAPEUTICS, INC. (US) | 2005-08-11 | — | — | WO | disclosed |