Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481972 | 0.91 | GRIN2B (0.59) | GRIN2BL3MBTL1ATMGRIN2AALDH1A1 | |
| SCHEMBL11663107 | 0.88 | ALOX15 (0.47) | GRIN2BL3MBTL1ATMALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11654776 | 0.86 | ALOX15 (0.46) | GRIN2BL3MBTL1ATMALOX15ALDH1A1 | |
| SCHEMBL6375003 | 0.84 | GRIN2B (0.55) | GRIN2BATMGRIN2AALDH1A1MEN1 | |
| SCHEMBL8583074 | 0.83 | ATM (0.61) | GRIN2BL3MBTL1ATMALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7331599 | 0.77 | GRIN2B (0.54) | GRIN2BL3MBTL1GRIN2AALDH1A1MEN1 | |
| SCHEMBL15362563 | 0.76 | ALDH1A1 (0.68) | L3MBTL1ALDH1A1MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL7323559 | 0.76 | GRIN2B (0.71) | GRIN2BL3MBTL1GRIN2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7320117 | 0.75 | GRIN2B (0.52) | GRIN2BGRIN2AMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL7329252 | 0.73 | GRIN2B (0.55) | GRIN2BL3MBTL1GRIN2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62153276-A | — | — | None | — | — | JP | disclosed |
| US-5912258-A | ANTISECRETORY AGENTS; GASTROINTESTINAL DISORDERS | SHISEIDO CO., LTD. (JP) | 1999-06-15 | — | — | US | disclosed |
| JP-S62153276-A | NITROGEN-CONTAINING 5-MEMBERED HETEROCYCLIC COMPOUND AND PRODUCTION THEREOF | YAMANOUCHI PHARMACEUT CO LTD | 1987-07-08 | — | — | JP | disclosed |