Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6375085 | 1.00 | GRIK1 (0.44) | GRIK1CYP2D6TDP1EPHX1SLC1A3 | |
| SCHEMBL6375091 | 1.00 | GRIK1 (0.44) | GRIK1CYP2D6TDP1EPHX1SLC1A3 | |
| SCHEMBL25657697 | 0.82 | FAAH (0.44) | GRIK1 | |
| SCHEMBL25657696 | 0.82 | FAAH (0.44) | GRIK1 | |
| SCHEMBL25178685 | 0.82 | EPHX2 (0.44) | GRIK1GRIA2 | |
| SCHEMBL25185805 | 0.82 | EPHX2 (0.44) | GRIK1GRIA2 | |
| SCHEMBL13953141 | 0.81 | MMP2 (0.38) | TDP1MEN1KMT2A | |
| SCHEMBL13893883 | 0.81 | MMP2 (0.38) | TDP1MEN1KMT2A | |
| SCHEMBL8302932 | 0.80 | MAPT (0.43) | MEN1KMT2A | |
| SCHEMBL8302927 | 0.80 | MAPT (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003775-B1 | HEPATITIS C INHIBITOR PEPTIDES | BOEHRINGER INGELHEIM CA LTD (CA) | 2005-03-16 | — | — | EP | disclosed |
| US-6767991-B1 | PEPTIDES AND ANALOGS THEREOF; VIRAL PROTEASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH PEPTIDES AND RIBAVIRIN | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2004-07-27 | — | — | US | disclosed |