Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 4/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6295711 | 0.99 | POLB (0.61) | POLBTHRBSIGMAR1ACHEDRD3 | |
| Hydrochloric Acid SCHEMBL4840396 | 0.99 | POLB (0.61) | POLBTHRBSIGMAR1ACHEDRD3 | |
| Hydrochloric Acid SCHEMBL6219381 | 0.94 | SIGMAR1 (0.57) | POLBTHRBSIGMAR1ACHEDRD3 | |
| SCHEMBL4837431 | 0.93 | SIGMAR1 (0.57) | POLBSIGMAR1ACHEDRD3CHRM3 | |
| SCHEMBL4832532 | 0.91 | ACHE (0.58) | POLBSIGMAR1ACHECHRM3 | |
| SCHEMBL6191181 | 0.88 | POLB (0.59) | POLBTHRBSIGMAR1DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL4836733 | 0.88 | POLB (0.60) | POLBTHRB | |
| SCHEMBL4839910 | 0.86 | TP53 (0.55) | POLBTHRBSIGMAR1ACHEDRD3 | |
| Hydrochloric Acid SCHEMBL4832406 | 0.84 | POLB (0.58) | POLBTHRBSIGMAR1DRD3DRD2 | |
| SCHEMBL4842118 | 0.83 | ACHE (0.66) | POLBSIGMAR1ACHECHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023422-A2 | PRODUCTION AND USE OF IONIC LIQUIDS CONTAINING THIOCYANATO ANIONS | SOLVENT INNOVATION GMBH (DE) | 2005-03-17 | — | — | WO | disclosed |
| US-6855715-B1 | Serine protease inhibitors | ELI LILLY AND COMPANY (US) | 2005-02-15 | — | — | US | disclosed |
| EP-1192135-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1192132-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076970-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000076971-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |