Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 12/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5101397 | 0.96 | KDR (0.36) | KDRGALR3GAARAF1BRAF | |
| SCHEMBL6038445 | 0.90 | MCHR1 (0.37) | KDRGAAS1PR1 | |
| SCHEMBL6038814 | 0.90 | ASAH1 (0.36) | KDRS1PR1 | |
| SCHEMBL6038768 | 0.89 | SMN1; SMN2 (0.38) | KDRS1PR1 | |
| SCHEMBL6038632 | 0.89 | S1PR1 (0.35) | KDRGALR3GAARAF1BRAF | |
| SCHEMBL5105614 | 0.87 | S1PR1 (0.43) | KDRS1PR1 | |
| SCHEMBL5108441 | 0.87 | ASAH1 (0.37) | KDRS1PR1 | |
| SCHEMBL5107633 | 0.87 | MCHR1 (0.38) | KDRGAAMAOAMAOBS1PR1 | |
| SCHEMBL5113619 | 0.87 | GCK (0.40) | KDRRAF1BRAF | |
| SCHEMBL5108320 | 0.86 | KDR (0.38) | KDRS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1522540-A1 | AZAARENE DERIVATIVES | Eisai Co., Ltd. (JP) | 2005-04-13 | — | — | EP | disclosed |