Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038814 | 0.97 | ASAH1 (0.36) | ASAH1FGFR1S1PR1KDRSCN9A | |
| SCHEMBL5114299 | 0.95 | SMN1; SMN2 (0.39) | FGFR1S1PR1KDR | |
| SCHEMBL6038768 | 0.92 | SMN1; SMN2 (0.38) | FGFR1S1PR1KDR | |
| SCHEMBL5101397 | 0.90 | KDR (0.36) | S1PR1KDR | |
| SCHEMBL5105614 | 0.89 | S1PR1 (0.43) | ASAH1S1PR1KDR | |
| SCHEMBL5107633 | 0.89 | MCHR1 (0.38) | S1PR1KDR | |
| SCHEMBL5108444 | 0.88 | ASAH1 (0.37) | ASAH1FGFR1SCN9A | |
| SCHEMBL5108320 | 0.88 | KDR (0.38) | S1PR1KDR | |
| SCHEMBL5107877 | 0.87 | S1PR1 (0.35) | S1PR1KDR | |
| SCHEMBL6375561 | 0.87 | KDR (0.35) | S1PR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7468380-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| US-20070004764-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| US-7109219-B2 | Nitrogen-containing aromatic derivatives | EISAI CO., LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| US-20050187236-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187236-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | ASAH1 4726/4885FGFR1 595/4885S1PR1 2534/4885 |
| US-20070004764-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | ASAH1 4726/4885FGFR1 595/4885S1PR1 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.