Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGAV | P06756 | 3/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114299 | 0.97 | SMN1; SMN2 (0.39) | SMN1; SMN2S1PR1FGFR1ITGB3ITGAV | |
| SCHEMBL6038814 | 0.95 | ASAH1 (0.36) | S1PR1FGFR1KDR | |
| SCHEMBL5108441 | 0.92 | ASAH1 (0.37) | S1PR1FGFR1KDR | |
| SCHEMBL5114304 | 0.91 | FGFR1 (0.35) | FGFR1KDR | |
| SCHEMBL6038632 | 0.89 | S1PR1 (0.35) | S1PR1ITGB3ITGAVITGB5KDR | |
| SCHEMBL6375561 | 0.89 | KDR (0.35) | S1PR1KDR | |
| SCHEMBL5105614 | 0.88 | S1PR1 (0.43) | S1PR1ITGB3ITGAVKDR | |
| SCHEMBL6514499 | 0.88 | SMN1; SMN2 (0.37) | SMN1; SMN2S1PR1FGFR1ITGB3ITGAV | |
| SCHEMBL6038445 | 0.88 | MCHR1 (0.37) | SMN1; SMN2S1PR1TSHRKMT2AKDR | |
| SCHEMBL5107755 | 0.87 | ITGB3 (0.38) | SMN1; SMN2S1PR1FGFR1ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004029-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1522540-A1 | AZAARENE DERIVATIVES | Eisai Co., Ltd. (JP) | 2005-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004029-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | SMN1; SMN2 3950/4885S1PR1 2534/4885FGFR1 595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.