Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106099 | 0.92 | HTT (0.58) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL6375580 | 0.90 | HTT (0.55) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL3480822 | 0.90 | ALDH1A1 (0.58) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL10020888 | 0.90 | HTT (0.59) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL6376231 | 0.89 | HTT (0.58) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL6815710 | 0.89 | HTT (0.58) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL4799531 | 0.89 | HTT (0.58) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL9073829 | 0.87 | HTT (0.56) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL11555366 | 0.86 | HTT (0.55) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL5330357 | 0.85 | HTT (0.50) | HTTTDP1ALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120141398-A1 | HAIR DYE CONTAINING ONE OR MORE EDIBLE OR COSMETIC COLORS | CHUANG KUO SHENG (TW) | 2012-06-07 | — | — | US | disclosed |
| WO-2009140163-A1 | OXAZOLOBENZIMIDAZOLE DERIVATIVES | MERCK & CO., INC. (US) | 2009-11-19 | — | — | WO | disclosed |
| EP-0688767-A1 | 5-mercapto-2-nitro paraphenylenediamine compounds and hair dye compositions containing same | Bristol-Myers Squibb Company (US) | 1995-12-27 | — | — | EP | disclosed |
| US-5091581-A | Reacting diaminonitrobenzene with chloroalkyl chloroformate | HANS SCHWARZKOPF GMBH (DE) | 1992-02-25 | — | — | US | disclosed |
| EP-0203446-A1 | Nitro-p-phenylene diamine derivatives, process for their preparation and hair dye compositions containing these compounds | Wella Aktiengesellschaft (DE) | 1986-12-03 | — | — | EP | disclosed |
| US-3957860-A | SULFAMIC ACID | CIBA-GEIGY AG (CH) | 1976-05-18 | — | — | US | disclosed |
| US-3930792-A | NITROAMINOBENZENE, QUATERNARY AMINE, N-OXYALKYLATED FATTY ACID AMIDES | CLAIROL INCORPORATED (US) | 1976-01-06 | — | — | US | disclosed |