Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.58 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.58 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.58 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 6/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 4/20 | 0.50 |
| ▸ | CPA1 | P15085 | 3/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12434361 | 0.99 | CHRNB2 (0.59) | LMNATDP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6562811 | 0.99 | CHRNB2 (0.59) | LMNATDP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9830046 | 0.99 | CHRNB2 (0.59) | LMNATDP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9234559 | 0.88 | LMNA (0.73) | LMNATDP1MMEACECPA1 | |
| SCHEMBL5612699 | 0.88 | LMNA (0.73) | LMNATDP1MMEACECPA1 | |
| SCHEMBL10665563 | 0.88 | LMNA (0.73) | LMNATDP1MMEACECPA1 | |
| SCHEMBL16452925 | 0.87 | LMNA (0.57) | LMNATDP1MMEACECPA1 | |
| SCHEMBL11393496 | 0.87 | LMNA (0.57) | LMNATDP1MMEACECPA1 | |
| SCHEMBL11393501 | 0.87 | LMNA (0.57) | LMNATDP1MMEACECPA1 | |
| SCHEMBL7778087 | 0.87 | LMNA (0.71) | LMNATDP1MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903075-B1 | Heterocyclic amide compounds as cell adhesion inhibitors | MERCK & CO., INC. (US) | 2005-06-07 | — | — | US | disclosed |
| WO-1999064395-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-12-16 | — | — | WO | disclosed |