Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Kebuzone SCHEMBL231224 | 0.98 | LMNA (0.58) | LMNAPTGS1ABCB11ALDH1A1MAPT | |
| SCHEMBL11809494 | 0.91 | ALDH1A1 (0.68) | LMNAPTGS1ABCB11ALDH1A1MAPT | |
| SCHEMBL28552048 | 0.84 | LMNA (0.56) | LMNAPTGS1ABCB11ALDH1A1MAPT | |
| SCHEMBL11329439 | 0.83 | ALDH1A1 (0.57) | LMNAPTGS1ABCB11ALDH1A1MAPT | |
| SCHEMBL21694463 | 0.81 | LMNA (0.61) | LMNAPTGS1ABCB11ALDH1A1MAPT | |
| Tribuzone SCHEMBL2109159 | 0.81 | ALDH1A1 (0.52) | LMNAPTGS1ABCB11ALDH1A1MAPT | |
| SCHEMBL11321102 | 0.81 | ALDH1A1 (0.52) | LMNAPTGS1ABCB11ALDH1A1MAPT | |
| SCHEMBL11332855 | 0.81 | CYP3A4 (0.51) | LMNAPTGS1ABCB11ALDH1A1MAPT | |
| SCHEMBL11327797 | 0.80 | ALDH1A1 (0.51) | LMNAPTGS1ABCB11ALDH1A1MAPT | |
| Phenylbutazone SCHEMBL10822155 | 0.80 | LMNA (0.64) | LMNAPTGS1ABCB11ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054556-A1 | Antiphlogistic agent and the use thereof | KOSMAS KG (DE) | 2005-03-10 | — | — | US | disclosed |