Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.33 |
| ▸ | HTR3B | O95264 | 3/20 | 0.33 |
| ▸ | HTR3A | P46098 | 3/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17610091 | 0.77 | GRIN2B (0.49) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6379561 | 0.77 | GRIN2B (0.49) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10183489 | 0.77 | ALDH1A1 (0.48) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2722842 | 0.77 | ALDH1A1 (0.48) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2722843 | 0.77 | ALDH1A1 (0.48) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5329 | 0.74 | GRIN2D (0.53) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29789768 | 0.74 | GRIN2D (0.53) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31469904 | 0.73 | ALOX5 (0.47) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31383621 | 0.73 | ALOX5 (0.47) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7394734 | 0.73 | PRKCQ (0.48) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1217001-B1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | EISAI CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6599917-B1 | A squalene-synthesizing enzyme inhibitor, a cholesterol biosynthesis inhibitor and a triglyceride biosynthesis inhibitor | EISAI CO., LTD. (JP) | 2003-07-29 | — | — | US | disclosed |
| EP-1217001-A1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |