Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643737 | 0.98 | GABRA1 (0.43) | GABRA1GABRB2MAPTALDH1A1MGLL | |
| Iodide SCHEMBL1502860 | 0.96 | GABRA1 (0.41) | GABRA1GABRB2MAPTALDH1A1MGLL | |
| Hydrazine SCHEMBL10865940 | 0.96 | GABRA1 (0.41) | GABRA1GABRB2MAPTALDH1A1MGLL | |
| Benzene SCHEMBL29130110 | 0.96 | GABRA1 (0.41) | GABRA1GABRB2MAPTALDH1A1MGLL | |
| Fluoride SCHEMBL1502835 | 0.96 | GABRA1 (0.41) | GABRA1GABRB2MAPTALDH1A1MGLL | |
| Water SCHEMBL187638 | 0.96 | GABRA1 (0.41) | GABRA1GABRB2MAPTALDH1A1MGLL | |
| Water SCHEMBL1973854 | 0.96 | GABRA1 (0.41) | GABRA1GABRB2MAPTALDH1A1MGLL | |
| Hydrochloric Acid SCHEMBL77688 | 0.96 | GABRA1 (0.41) | GABRA1GABRB2MAPTALDH1A1MGLL | |
| Cyanide SCHEMBL4048234 | 0.94 | GABRA1 (0.40) | GABRA1GABRB2MAPTALDH1A1MGLL | |
| Alcohol SCHEMBL28273112 | 0.90 | GABRA1 (0.42) | GABRA1GABRB2MAPTALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 985 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874616-B | Organic intermediate and preparation method and application thereof | 四川美域高生物医药科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| US-20250163010-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-05-22 | — | — | US | claimed |
| CN-119874616-A | Novel organic intermediate and preparation method and application thereof | 四川美域高生物医药科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119504719-A | Synthesis method of 3-ethyl-3- [ (2-oxiranylmethoxy) methyl ] oxetane | 湖北荆洪生物科技股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119504660-A | Method for preparing 3,3' - [1, 4-butyl bis (oxymethylene) ] -bis- (3-ethyl) oxetane | 湖北荆洪生物科技股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119350225-A | Synthesis method of hydrogen storage material N-ethyl carbazole | 连云港海迪化工科技有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-119081437-A | Artificial board based on soybean-based adhesive and agricultural waste and preparation method thereof | 华南农业大学 | 2024-12-06 | — | — | CN | claimed |
| CN-118715213-A | Process for preparing N- (1-methylcyclopropyl) -2- (3-pyridinyl) -2H-indazole-4-carboxamide and intermediates thereof | FMC公司 | 2024-09-27 | — | — | CN | claimed |
| CN-115572229-B | Preparation method of polymerizable photoinitiator based on alpha-hydroxyketone | 江苏三木化工股份有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-116003965-B | Prepreg toughening layer | 中国石油化工股份有限公司 | 2024-07-23 | — | — | CN | claimed |
| US-6515128-B2 | Dissolving 6-hydroxy-3,4-dihydroquinolinone and a base in water; dissolving a 1-cyclohexyl-5- (4-halobutyl)-tetrazole in water-immiscible solvent, mixing aqueous phase and organic phase in presence of phase transfer catalyst; recovering | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-02-04 | — | — | US | claimed |
| US-20020099213-A1 | Processes for preparing cilostazol | TEVA PHARMACEUTICALS USA, INC. | 2002-07-25 | — | — | US | claimed |
| WO-2002014283-A1 | PROCESSES FOR PREPARING CILOSTAZOL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2002-02-21 | — | — | WO | claimed |
| US-5929233-A | HALOGENATION OF ALLENYL BETA-LACTAM IN PRESENCE OF SULFINATE ION OR THIOLATE ION CAPTURING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-07-27 | — | — | US | claimed |
| US-4889927-A | REACTING ACYL-SUBSTITUTED GLYCOSE WITH ALKALI METAL HYDRIDE, HYDROLYSIS | JUJO PAPER CO., LTD. (JP) | 1989-12-26 | — | — | US | claimed |
| EP-0004570-B1 | THIOL ESTERS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND A PROCESS FOR PREPARING CEPHALOSPORIN COMPOUNDS USING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-04-14 | — | — | EP | claimed |
| US-4293702-A | FROM 2-ALKOXYBENZOTHIAZOLES; CATALYST OF TERTIARY AMINE, QUATERNARY AMMONIUM COMPOUND OR DIALKYL SULFATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-06 | — | — | US | claimed |
| EP-0004570-A1 | Thiol esters, process for their preparation, pharmaceutical compositions containing them and a process for preparing cephalosporin compounds using the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1979-10-17 | — | — | EP | claimed |
| US-4144264-A | Process for producing a 3-methyl-2-(4-halophenyl)butyronitrile | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-03-13 | — | — | US | claimed |
| US-4012428-A | Method for preparing 3-methyl-2-(4-halogenophenyl)-butyronitrile | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099213-A1 | Processes for preparing cilostazol | PDE3A, PDE12, PDE5A | GABRA1 2891/4885GABRB2 4041/4885MAPT 3372/4885 |
| US-20250163010-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | ACHE, CYP4B1, CYP3A4 | GABRA1 1549/4885GABRB2 1584/4885MAPT 4220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.