Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 3/20 | 0.48 |
| ▸ | DRD1 | P21728 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6363645 | 1.00 | ABCB11 (0.48) | ABCB11DRD1CYP2C19ADRA2ACYP2B6 | |
| Sulfuric Acid SCHEMBL6363639 | 0.96 | ABCB11 (0.50) | ABCB11DRD1CYP2C19ADRA2ACYP2B6 | |
| Sulfuric Acid SCHEMBL951856 | 0.96 | ABCB11 (0.50) | ABCB11DRD1CYP2C19ADRA2ACYP2B6 | |
| SCHEMBL954553 | 0.94 | DRD1 (0.47) | ABCB11DRD1CYP2C19ADRA2ACYP2B6 | |
| SCHEMBL1269320 | 0.94 | DRD1 (0.47) | ABCB11DRD1CYP2C19ADRA2ACYP2B6 | |
| Hydrochloric Acid SCHEMBL3077705 | 0.93 | DRD1 (0.46) | ABCB11DRD1CYP2C19ADRA2ACYP2B6 | |
| Bromide SCHEMBL2087060 | 0.93 | DRD1 (0.46) | ABCB11DRD1CYP2C19ADRA2ACYP2B6 | |
| Hydrochloric Acid SCHEMBL3077710 | 0.93 | DRD1 (0.46) | ABCB11DRD1CYP2C19ADRA2ACYP2B6 | |
| Hydrochloric Acid SCHEMBL6615615 | 0.92 | DRD1 (0.45) | ABCB11DRD1CYP2C19ADRA2ACYP2B6 | |
| SCHEMBL5024497 | 0.88 | ABCB11 (0.42) | ABCB11DRD1CYP2C19ADRA2ACYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059696-A1 | Process for the recovery of S -(+)-methyl- (2-chlorophenyl)- (6,7-dihydro- 4H-thieno [3,2-c] pyrid-5-yl) acetate hydrogen sulfate (clopidogrel bisulfate) from its (R) and mixture of (R) and (S)- isomers | DR. REDDY'S LABORATORIES LIMITED | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059696-A1 | Process for the recovery of S -(+)-methyl- (2-chlorophenyl)- (6,7-dihydro- 4H-thieno [3,2-c] pyrid-5-yl) acetate hydrogen sulfate (clopidogrel bisulfate) from its (R) and mixture of (R) and (S)- isomers | P2RY13, P2RY11, P2RY6 | ABCB11 1638/4885DRD1 2842/4885CYP2C19 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.