SCHEMBL954553

SCHEMBL954553

CC(C(=O)O)(c1ccccc1Cl)N1CCc2sccc2C1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 4/20 0.47
ABCB11 O95342 3/20 0.47
CYP2C19 P33261 3/20 0.47
ADRA2A P08913 2/20 0.47
CYP2B6 P20813 2/20 0.47
OPRM1 P35372 2/20 0.47
OPRK1 P41145 2/20 0.47
HTR2B P41595 2/20 0.47
KCNH2 Q12809 2/20 0.47
THRB P10828 1/20 0.47
NR1I2 O75469 1/20 0.47
CHRM2 P08172 1/20 0.47
HTR2A P28223 1/20 0.47
SLC6A4 P31645 1/20 0.47
P2RY12 Q9H244 1/20 0.47
DRD4 P21917 2/20 0.44
DRD3 P35462 2/20 0.44
ALDH1A1 P00352 2/20 0.44
USP2 O75604 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1269320 1.00 DRD1 (0.47) DRD1ABCB11CYP2C19ADRA2ACYP2B6
Hydrochloric Acid SCHEMBL3077710 0.99 DRD1 (0.46) DRD1ABCB11CYP2C19ADRA2ACYP2B6
Hydrochloric Acid SCHEMBL3077705 0.99 DRD1 (0.46) DRD1ABCB11CYP2C19ADRA2ACYP2B6
Bromide SCHEMBL2087060 0.99 DRD1 (0.46) DRD1ABCB11CYP2C19ADRA2ACYP2B6
Hydrochloric Acid SCHEMBL6615615 0.98 DRD1 (0.45) DRD1ABCB11CYP2C19ADRA2ACYP2B6
Sulfuric Acid SCHEMBL951856 0.96 ABCB11 (0.50) DRD1ABCB11CYP2C19ADRA2ACYP2B6
Sulfuric Acid SCHEMBL6363639 0.96 ABCB11 (0.50) DRD1ABCB11CYP2C19ADRA2ACYP2B6
Sulfuric Acid SCHEMBL6363645 0.94 ABCB11 (0.48) DRD1ABCB11CYP2C19ADRA2ACYP2B6
Sulfuric Acid SCHEMBL6375982 0.94 ABCB11 (0.48) DRD1ABCB11CYP2C19ADRA2ACYP2B6
SCHEMBL5024497 0.88 ABCB11 (0.42) DRD1ABCB11CYP2C19ADRA2ACYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4330382-A2 IN VITRO DRUGS FROM PRODRUGS AND USE THEREOF Brandenburgische Technische Universität Cottbus-Senftenberg (DE) 2024-03-06 EP claimed
JP-4681545-B2 2011-05-11 JP claimed
US-20050113406-A1 Polymorphs of clopidogrel hydrochloride and their use as antithrombic compounds EGIS GYOGYSZERGYAR RT. (HU) 2005-05-26 US claimed
WO-2004108665-A2 A PROCESS FOR PREPARATION OF CLOPIDOGREL SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2004-12-16 WO claimed
EP-1474427-A1 POLYMORPHS OF CLOPIDOGREL HYDROCHLORIDE AND THEIR USE AS ANTITHROMBIC COMPOUNDS EGIS GYOGYSZERGYAR (HU) 2004-11-10 EP claimed
EP-1438314-A1 A PROCESS FOR PREPARING ENANTIOMERICALLY PURE ALPHA-PHENYL-APLPHA(6,7-DIHYDRO-4H-THIENO 3,2-C PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES Merck Generics (UK) Limited (GB) 2004-07-21 EP claimed
WO-2003066637-A1 POLYMORPHS OF CLOPIDOGREL HYDROCHLORIDE AND THEIR USE AS ANTITHROMBIC COMPOUNDS EGIS Gyógyszergyár Rt. (HU) 2003-08-14 WO claimed
WO-2003035652-A1 A PROCESS FOR PREPARING ENANTIOMERICALLY PURE α-PHENYL-α-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES MERCK GENERICS [UK] LIMITED (GB) 2003-05-01 WO claimed
US-20240016785-A1 CLOPIDOGREL FOR USE IN THE TREATMENT OF FOCAL SEGMENTAL GLOMERULOSCLEROSIS (FSGS) DELTA 4 GMBH (AT) 2024-01-18 US disclosed
EP-1837337-B1 Novel crystalline polymorphs of clopidogrel GENERICS UK LTD (GB) 2016-04-06 EP disclosed
EP-1772456-B1 Novel crystalline polymorphs of clopidogrel GENERICS UK LTD (GB) 2014-10-29 EP disclosed
WO-2011149110-A1 NOVEL COMPOSITION FOR THE PREVENTION AND/OR TREATMENT OF THROMBOEMBOLISM DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-12-01 WO disclosed
WO-2011101865-A2 STABLE PHARMACEUTICAL COMPOSITIONS OF CLOPIDOGREL FOR PARENTERAL DELIVERY CADILA HEALTHCARE LIMITED (IN) 2011-08-25 WO disclosed
US-7897613-B2 Crystalline polymorphs of clopidogrel GENERICS [UK] LIMITED (GB) 2011-03-01 US disclosed
WO-2004108665-A2 A PROCESS FOR PREPARATION OF CLOPIDOGREL SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2004-12-16 WO disclosed
EP-1474427-A1 POLYMORPHS OF CLOPIDOGREL HYDROCHLORIDE AND THEIR USE AS ANTITHROMBIC COMPOUNDS EGIS GYOGYSZERGYAR (HU) 2004-11-10 EP disclosed
WO-2003035652-A9 A PROCESS FOR PREPARING ENANTIOMERICALLY PURE α-PHENYL-α-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES MERCK GENERICS UK LTD (GB) 2004-04-08 WO disclosed
WO-2003066637-A1 POLYMORPHS OF CLOPIDOGREL HYDROCHLORIDE AND THEIR USE AS ANTITHROMBIC COMPOUNDS EGIS Gyógyszergyár Rt. (HU) 2003-08-14 WO disclosed
EP-0281459-B1 Dextrorotatory enantiomer of alpha-(4,5,6,7-tetrahydrothieno[3,2-c]pyrid-5-yl)(2-chlorophenyl)methyl acetate, process for its preparation and pharmaceutical compositions containing it SANOFI SA (FR) 1995-04-26 EP disclosed
EP-0281459-A1 Dextrorotatory enantiomer of alpha-(4,5,6,7-tetrahydrothieno[3,2-c]pyrid-5-yl)(2-chlorophenyl)methyl acetate, process for its preparation and pharmaceutical compositions containing it SANOFI (FR) 1988-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113406-A1 Polymorphs of clopidogrel hydrochloride and their use as antithrombic compounds PLAT, PFKP, P2RY6 DRD1 3227/4885ABCB11 263/4885CYP2C19 12/4885
US-20240016785-A1 CLOPIDOGREL FOR USE IN THE TREATMENT OF FOCAL SEGMENTAL GLOMERULOSCLEROSIS (FSGS) P2RY13, REN, PDGFRB DRD1 4267/4885ABCB11 962/4885CYP2C19 643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.