Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585937 | 0.85 | ALDH1A1 (0.36) | TSHRKDM4ETDP1 | |
| SCHEMBL12371266 | 0.83 | HRH3 (0.51) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL8584708 | 0.81 | ALDH1A1 (0.38) | HRH3SMN1; SMN2TSHRKDM4E | |
| SCHEMBL27372825 | 0.81 | HRH3 (0.40) | HRH3SMN1; SMN2SLC6A2HRH1CHRM2 | |
| SCHEMBL1277024 | 0.81 | HRH3 (0.54) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL20231219 | 0.81 | ALDH1A1 (0.45) | HRH3SIGMAR1KDM4E | |
| Bromide SCHEMBL2336286 | 0.81 | HRH3 (0.50) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL20325465 | 0.79 | HRH3 (0.39) | HRH3SMN1; SMN2SLC6A2HRH1CHRM2 | |
| Iodide SCHEMBL2333886 | 0.79 | HRH3 (0.52) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL13334883 | 0.79 | HRH3 (0.37) | HRH3SLC6A2HRH1CHRM2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171480-B1 | METHOD FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2005-05-25 | — | — | EP | disclosed |
| US-6803431-B1 | COMPLEX OF A TRANSITION METAL WITH A TRIDENTATE MACROCYCLIC LIGAND WHICH BEARS AT LEAST ONE SUBSTITUENT HAVING A DONOR FUNCTION AND AN ALUMINOXANE | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-12 | — | — | US | disclosed |