Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | HAT1 | O14929 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376260 | 1.00 | F10 (0.47) | F10ALDH1A1HTTEP300KDM4E | |
| SCHEMBL5632366 | 0.90 | ALDH1A1 (0.46) | F10ALDH1A1HTTEP300KDM4E | |
| SCHEMBL5631658 | 0.89 | ALDH1A1 (0.46) | ALDH1A1HTTEP300KDM4ERECQL | |
| SCHEMBL5631652 | 0.89 | ALDH1A1 (0.46) | ALDH1A1HTTEP300KDM4ERECQL | |
| SCHEMBL5631611 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HTTEP300KDM4ERECQL | |
| SCHEMBL5633981 | 0.87 | ALDH1A1 (0.42) | F10ALDH1A1HTTEP300KDM4E | |
| SCHEMBL5633994 | 0.87 | ALDH1A1 (0.42) | F10ALDH1A1HTTEP300KDM4E | |
| SCHEMBL5633986 | 0.87 | ALDH1A1 (0.42) | F10ALDH1A1HTTEP300KDM4E | |
| SCHEMBL6372830 | 0.86 | F10 (0.59) | F10ALDH1A1EP300KDM4ELMNA | |
| SCHEMBL5429259 | 0.86 | F10 (0.59) | F10ALDH1A1EP300KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137230-A1 | Carboxamide derivatives | DORSCH DIETER (DE) | 2005-06-23 | — | — | US | claimed |
| US-20040038858-A1 | Carboxamide derivatives and their use in the treatment of thromboembolic diseases and tumours | MERCK PATENT GMBH (DE) | 2004-02-26 | — | — | US | claimed |
| US-20050137230-A1 | Carboxamide derivatives | DORSCH DIETER (DE) | 2005-06-23 | — | — | US | disclosed |
| US-20040038858-A1 | Carboxamide derivatives and their use in the treatment of thromboembolic diseases and tumours | MERCK PATENT GMBH (DE) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137230-A1 | Carboxamide derivatives | F11, F12, F2 | F10 4/4885ALDH1A1 832/4885HTT 4519/4885 |
| US-20040038858-A1 | Carboxamide derivatives and their use in the treatment of thromboembolic diseases and tumours | CNR2, CNR1, HCAR2 | F10 117/4885ALDH1A1 1757/4885HTT 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.