Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 18/20 | 0.55 |
| ▸ | FPR2 | P25090 | 18/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6374720 | 0.86 | F10 (0.58) | FPR2 | |
| SCHEMBL6374712 | 0.86 | F10 (0.58) | FPR2 | |
| SCHEMBL6376598 | 0.86 | F10 (0.58) | FPR2 | |
| SCHEMBL6374212 | 0.83 | F10 (0.56) | FPR2 | |
| SCHEMBL6374263 | 0.83 | F10 (0.56) | FPR2 | |
| SCHEMBL6374223 | 0.83 | F10 (0.56) | FPR2 | |
| SCHEMBL6379444 | 0.82 | F10 (0.57) | FPR2 | |
| SCHEMBL5433595 | 0.78 | F10 (0.56) | — | |
| SCHEMBL5434232 | 0.76 | F10 (0.60) | FPR1FPR2 | |
| SCHEMBL6329234 | 0.75 | SMN1; SMN2 (0.42) | FPR1FPR2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137230-A1 | Carboxamide derivatives | DORSCH DIETER (DE) | 2005-06-23 | — | — | US | claimed |
| US-20040038858-A1 | Carboxamide derivatives and their use in the treatment of thromboembolic diseases and tumours | MERCK PATENT GMBH (DE) | 2004-02-26 | — | — | US | claimed |
| US-20050137230-A1 | Carboxamide derivatives | DORSCH DIETER (DE) | 2005-06-23 | — | — | US | disclosed |
| US-20040038858-A1 | Carboxamide derivatives and their use in the treatment of thromboembolic diseases and tumours | MERCK PATENT GMBH (DE) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137230-A1 | Carboxamide derivatives | F11, F12, F2 | FPR1 113/4885FPR2 766/4885CHRM3 2693/4885 |
| US-20040038858-A1 | Carboxamide derivatives and their use in the treatment of thromboembolic diseases and tumours | CNR2, CNR1, HCAR2 | FPR1 429/4885FPR2 176/4885CHRM3 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.