Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PPM1D | O15297 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376555 | 0.81 | KDM4E (0.42) | HDAC1KDM4EGAAHPGDALDH1A1 | |
| SCHEMBL6379060 | 0.73 | ITGB3 (0.34) | ITGB3ITGB1ITGAVITGA5SMN1; SMN2 | |
| SCHEMBL5862834 | 0.72 | HPGD (0.56) | EPHX1HPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7642028 | 0.72 | GAA (0.49) | KDM4EGAAHPGDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11619519 | 0.70 | CYP3A4 (0.49) | HDAC1ALOX15KDM4EGAAHPGD | |
| Hydrochloric Acid SCHEMBL11617273 | 0.69 | SLC2A1 (0.39) | HDAC1ALOX15KDM4EGAAHPGD | |
| SCHEMBL11622516 | 0.69 | ABCB11 (0.48) | KDM4EGAAALDH1A1MAPTHTT | |
| SCHEMBL27570765 | 0.68 | AAK1 (0.56) | CTSL | |
| SCHEMBL11618210 | 0.68 | CDC25B (0.46) | KDM4EGAAHPGDALDH1A1MAPT | |
| SCHEMBL1560414 | 0.68 | MAPT (0.54) | KDM4EGAAHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225895-B1 | FAB I INHIBITORS | AFFINIUM PHARM INC (CA) | 2005-05-04 | — | — | EP | disclosed |
| US-6762201-B1 | SUCH AS N-((2-AMINO-5-(N-METHYL-N-((1-METHYLINDOL-2-YL) -METHYL)CARBAMOYL)PHENYL)METHYL)-N-METHYLACETAMIDE; BACTERIAL INFECTIONS | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2004-07-13 | — | — | US | disclosed |
| EP-1225895-A4 | FAB I INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-1225895-A1 | FAB I INHIBITORS | SmithKline Beecham Corporation (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001026654-A1 | FAB I INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-04-19 | — | — | WO | disclosed |