Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6374373 | 0.82 | PPARA (0.53) | PPARAPOLBALDH1A1MAPK1KDM4E | |
| SCHEMBL6373707 | 0.81 | KMT2A (0.52) | MEN1KMT2APOLBALDH1A1TDP1 | |
| SCHEMBL6376069 | 0.80 | ALDH1A1 (0.59) | MEN1KMT2APOLBALDH1A1TDP1 | |
| SCHEMBL6376171 | 0.80 | KMT2A (0.51) | MEN1KMT2APOLBALDH1A1TDP1 | |
| SCHEMBL6160019 | 0.79 | KMT2A (0.52) | MEN1KMT2APOLBALDH1A1TDP1 | |
| SCHEMBL27478271 | 0.78 | KMT2A (0.49) | MEN1KMT2APOLBALDH1A1TDP1 | |
| SCHEMBL5332908 | 0.77 | KMT2A (0.57) | MEN1KMT2APOLBALDH1A1TDP1 | |
| SCHEMBL14212007 | 0.77 | ALDH1A1 (0.55) | MEN1KMT2APOLBALDH1A1NPC1 | |
| SCHEMBL23182775 | 0.76 | KMT2A (0.55) | MEN1KMT2APOLBALDH1A1TDP1 | |
| SCHEMBL21901813 | 0.76 | TSHR (0.54) | MEN1KMT2APOLBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184366-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA(PPAR) | KYORIN SEIYAKU KK (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-6506797-B1 | Activate by binding to receptor as ligands of human peroxisome preliferant-activated receptor alpha alpha ), and exhibit potent decreasing action on lipids in blood (cholesterol and triglyceride). | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-01-14 | — | — | US | disclosed |
| EP-1184366-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA(PPAR) | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-03-06 | — | — | EP | disclosed |