Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14212007 | 0.85 | ALDH1A1 (0.55) | ALDH1A1POLBLDHA | |
| SCHEMBL6377176 | 0.82 | PPARA (0.46) | PPARAALDH1A1KDM4EHPGDMAPK1 | |
| SCHEMBL7839814 | 0.82 | HPGD (0.45) | PPARAALDH1A1HPGDPOLB | |
| SCHEMBL15448867 | 0.81 | PPARA (0.43) | PPARAALDH1A1LDHA | |
| SCHEMBL6866159 | 0.78 | CFD (0.70) | PPARAMRGPRX4CFDPPARGALDH1A1 | |
| SCHEMBL11509018 | 0.78 | PTPRB (0.47) | — | |
| SCHEMBL6376504 | 0.77 | PPARA (0.84) | PPARAPPARG | |
| SCHEMBL5145379 | 0.77 | MRGPRX4 (0.55) | PPARAMRGPRX4CFDPPARGALDH1A1 | |
| SCHEMBL20522149 | 0.77 | PPARG (0.60) | PPARAMRGPRX4CFDPPARGALDH1A1 | |
| SCHEMBL12837926 | 0.77 | MRGPRX4 (0.57) | PPARAMRGPRX4CFDPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184366-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA(PPAR) | KYORIN SEIYAKU KK (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-6506797-B1 | Activate by binding to receptor as ligands of human peroxisome preliferant-activated receptor alpha alpha ), and exhibit potent decreasing action on lipids in blood (cholesterol and triglyceride). | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-01-14 | — | — | US | disclosed |
| EP-1184366-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA(PPAR) | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-03-06 | — | — | EP | disclosed |