Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16105797 | 0.83 | HTR2A (0.46) | HTR2AHTR2BHTR2CKIF11TAAR1 | |
| SCHEMBL5358396 | 0.83 | HTR2A (0.46) | HTR2AHTR2BHTR2CKIF11TAAR1 | |
| SCHEMBL14339435 | 0.83 | KIF11 (0.47) | HTR2AHTR2BHTR2CKIF11TAAR1 | |
| SCHEMBL46757 | 0.83 | HTR2A (0.63) | HTR2AHTR2BHTR2CTAAR1SIGMAR1 | |
| SCHEMBL10233507 | 0.82 | HTR2A (0.44) | HTR2AHTR2BHTR2CKIF11TAAR1 | |
| Ammonia Solution, Strong SCHEMBL266843 | 0.81 | HTR2A (0.61) | HTR2AHTR2BHTR2CTAAR1SIGMAR1 | |
| SCHEMBL20811436 | 0.81 | HTR2A (0.47) | HTR2AHTR2BHTR2CKIF11TAAR1 | |
| SCHEMBL17805427 | 0.81 | HTR2A (0.47) | HTR2AHTR2BHTR2CKIF11TAAR1 | |
| SCHEMBL128188 | 0.80 | RORC (0.50) | HTR2AHTR2BHTR2C | |
| SCHEMBL23749962 | 0.79 | HTR2A (0.47) | HTR2AHTR2BHTR2CKIF11TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1548023-B1 | Transition metal compound, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2013-08-14 | — | — | EP | disclosed |
| EP-1548037-A2 | Random propylene-ethylene copolymers | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |