Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957686 | 0.89 | MMP2 (0.46) | SMN1; SMN2L3MBTL1MAPTLMNAMMP2 | |
| SCHEMBL2274363 | 0.87 | L3MBTL1 (0.40) | SMN1; SMN2L3MBTL1MAPTLMNAMMP2 | |
| SCHEMBL14271452 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1MAPTLMNAMMP2 | |
| SCHEMBL4653743 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1MAPTLMNAMMP2 | |
| SCHEMBL4955666 | 0.84 | MMP2 (0.42) | SMN1; SMN2L3MBTL1MAPTMMP2MMP9 | |
| SCHEMBL4960020 | 0.83 | MMP2 (0.47) | L3MBTL1MAPTMMP2MMP9HDAC3 | |
| SCHEMBL19809645 | 0.83 | MMP2 (0.47) | L3MBTL1MAPTMMP2MMP9HDAC3 | |
| SCHEMBL6378260 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1MAPTLMNAMMP2 | |
| SCHEMBL4654777 | 0.82 | MAPT (0.40) | SMN1; SMN2L3MBTL1MAPTLMNAMMP2 | |
| SCHEMBL14271433 | 0.82 | MAPT (0.40) | SMN1; SMN2L3MBTL1MAPTLMNAMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838074-B2 | Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-01-04 | — | — | US | disclosed |