Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378470 | 1.00 | SERPINE1 (0.64) | SERPINE1ALDH1A1HRH3PTGS2PTPN1 | |
| SCHEMBL6372934 | 0.87 | SERPINE1 (0.74) | SERPINE1ALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL6372931 | 0.87 | SERPINE1 (0.74) | SERPINE1ALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL6373887 | 0.85 | SERPINE1 (0.78) | SERPINE1HRH3 | |
| SCHEMBL6373881 | 0.85 | SERPINE1 (0.78) | SERPINE1HRH3 | |
| SCHEMBL6375268 | 0.81 | SERPINE1 (0.70) | SERPINE1ALDH1A1HRH3ALOX5MEN1 | |
| SCHEMBL6375264 | 0.81 | SERPINE1 (0.70) | SERPINE1ALDH1A1HRH3ALOX5MEN1 | |
| Dimethylamine SCHEMBL6375602 | 0.80 | SERPINE1 (0.65) | SERPINE1ALDH1A1HRH3ALOX5MEN1 | |
| Dimethylamine SCHEMBL6374529 | 0.79 | SERPINE1 (0.63) | SERPINE1ALDH1A1HRH3ALOX5MEN1 | |
| SCHEMBL6372616 | 0.79 | SERPINE1 (1.00) | SERPINE1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050249681-A1 | Use of diketopiperazine derivatives as photostable uv-filters in cosmetic and pharmaceutical preparations | BASF AKTIENGESELLSCHAFT (DE) | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050249681-A1 | Use of diketopiperazine derivatives as photostable uv-filters in cosmetic and pharmaceutical preparations | DHPS, MC1R, MITF | SERPINE1 1257/4885ALDH1A1 1206/4885HRH3 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.