Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390272 | 0.77 | PIK3CD (0.43) | ALDH1A1CYP2C9TSHRADRA1DHTR6 | |
| SCHEMBL6376093 | 0.76 | KDM1A (0.50) | CYP3A4KDM1ASLC13A5MAOAMAOB | |
| SCHEMBL235980 | 0.76 | POLB (0.54) | L3MBTL1CYP3A4KDM1ASLC13A5MAOA | |
| SCHEMBL2203168 | 0.76 | POLB (0.54) | L3MBTL1CYP3A4KDM1ASLC13A5MAOA | |
| SCHEMBL6379419 | 0.75 | CYP2C9 (0.37) | L3MBTL1ALDH1A1CYP2C9TSHRMEN1 | |
| SCHEMBL91503 | 0.73 | SLC13A5 (0.50) | RAB9ANPC1L3MBTL1KDM1ASLC13A5 | |
| SCHEMBL6047280 | 0.73 | KDM1A (0.54) | CYP3A4CYP2C19KDM1ASLC13A5MAOA | |
| SCHEMBL30505689 | 0.72 | CYP2C9 (0.50) | RAB9ANPC1CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL5382166 | 0.72 | LTA4H (0.55) | RAB9ANPC1ALDH1A1CYP2C9MEN1 | |
| SCHEMBL27585504 | 0.72 | KDM1A (0.41) | L3MBTL1CYP3A4KDM1ASLC13A5MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1217001-B1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | EISAI CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6599917-B1 | A squalene-synthesizing enzyme inhibitor, a cholesterol biosynthesis inhibitor and a triglyceride biosynthesis inhibitor | EISAI CO., LTD. (JP) | 2003-07-29 | — | — | US | disclosed |
| EP-1217001-A1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |