Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370842 | 0.91 | TNF (0.30) | — | |
| SCHEMBL6377172 | 0.87 | KCNH2 (0.39) | PTPN11 | |
| SCHEMBL6378799 | 0.82 | KCNH2 (0.37) | — | |
| SCHEMBL6371179 | 0.81 | KCNH2 (0.35) | — | |
| SCHEMBL6372286 | 0.81 | — | — | |
| SCHEMBL6371437 | 0.81 | KCNH2 (0.42) | — | |
| SCHEMBL6371603 | 0.80 | KCNH2 (0.31) | — | |
| SCHEMBL6377863 | 0.80 | KCNH2 (0.33) | — | |
| SCHEMBL6371069 | 0.80 | EEF2K (0.34) | PTPN11LMNA | |
| SCHEMBL6370719 | 0.78 | KCNH2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096278-A1 | Antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-05 | — | — | US | claimed |
| US-20050096278-A1 | Antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096278-A1 | Antibacterial agents | MRPL21, FBL, SDHA | PTPN11 4043/4885LMNA 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.