⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379592 | 1.00 | — | — | |
| SCHEMBL8394901 | 0.86 | ALDH1A1 (0.50) | — | |
| SCHEMBL27548544 | 0.84 | ALDH1A1 (0.46) | — | |
| SCHEMBL8896217 | 0.83 | ALDH1A1 (0.54) | — | |
| SCHEMBL6379234 | 0.79 | ALDH1A1 (0.54) | — | |
| SCHEMBL18095951 | 0.78 | — | — | |
| SCHEMBL18095952 | 0.78 | — | — | |
| SCHEMBL11598670 | 0.77 | ALDH1A1 (0.37) | — | |
| SCHEMBL1702907 | 0.76 | — | — | |
| SCHEMBL9808441 | 0.76 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976734-B1 | Selective inhibitors of viral or bacterial neuraminidase | GILEAD SCIENCES INC (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20050176758-A1 | 2-(hydroxy or methoxymethoxy)-4-(carboxy or alkoxycarbonyl)-5-(fluoro or hydrogen)-7-oxabicyclo(4.1.0)hept-3-ene chemical intermediates to neuraminidase inhibitors | GILEAD SCIENCES, INC. | 2005-08-11 | — | — | US | disclosed |
| US-6225341-B1 | FOR INHIBITING NEURAMINIDASE; FOR THERAPY AND PROPHYLAXIS OF VIRUS INFECTION | GILEAD SCIENCES, INC. | 2001-05-01 | — | — | US | disclosed |
| EP-0759917-B1 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | GILEAD SCIENCES INC (US) | 2000-04-12 | — | — | EP | disclosed |
| EP-0759917-A1 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | GILEAD SCIENCES, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| US-4581178-A | USING TRANSITION METAL COMPLEXES CONTAINING PHOSPHINE OR ARSINE LI | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-08 | — | — | US | disclosed |