⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095951 | 1.00 | — | — | |
| SCHEMBL9808441 | 0.83 | ALDH1A1 (0.52) | — | |
| SCHEMBL6379592 | 0.78 | — | — | |
| SCHEMBL6379596 | 0.78 | — | — | |
| SCHEMBL1702907 | 0.78 | — | — | |
| SCHEMBL11444664 | 0.77 | ALDH1A1 (0.57) | — | |
| SCHEMBL27548544 | 0.76 | ALDH1A1 (0.46) | — | |
| SCHEMBL6470025 | 0.76 | — | — | |
| Nitric Acid SCHEMBL961471 | 0.75 | THRB (0.65) | — | |
| Nitric Acid SCHEMBL7919625 | 0.75 | THRB (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008358-B2 | Synthesis of desosamines | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200347087-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-11-05 | — | — | US | disclosed |
| US-10544182-B2 | Synthesis of desosamines | Presidents and Fellow of Harvard College (US) | 2020-01-28 | — | — | US | disclosed |
| US-20180111956-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-26 | — | — | US | disclosed |
| EP-3277701-A1 | SYNTHESIS OF DESOSAMINES | President and Fellows of Harvard College (US) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016154533-A1 | SYNTHESIS OF DESOSAMINES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-29 | — | — | WO | disclosed |