Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | ESRRG | P62508 | 4/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6375812 | 1.00 | LMNA (0.51) | LMNAHTR6ESR1ESR2CYP19A1 | |
| SCHEMBL6374434 | 0.94 | HTR6 (0.60) | LMNAHTR6ESR1ESR2CYP19A1 | |
| SCHEMBL6378282 | 0.94 | HTR6 (0.60) | LMNAHTR6ESR1ESR2CYP19A1 | |
| SCHEMBL6378738 | 0.94 | HTR6 (0.60) | LMNAHTR6ESR1ESR2CYP19A1 | |
| SCHEMBL5738607 | 0.88 | HTR6 (0.65) | LMNAHTR6ESR1ESR2CYP19A1 | |
| SCHEMBL5738610 | 0.88 | HTR6 (0.65) | LMNAHTR6ESR1ESR2CYP19A1 | |
| SCHEMBL5725712 | 0.86 | LMNA (0.59) | LMNAHTR6ESR1ESR2CYP19A1 | |
| SCHEMBL5725709 | 0.86 | LMNA (0.59) | LMNAHTR6ESR1ESR2CYP19A1 | |
| SCHEMBL5725707 | 0.86 | LMNA (0.59) | LMNAHTR6ESR1ESR2CYP19A1 | |
| SCHEMBL5739854 | 0.84 | LMNA (0.56) | LMNAHTR6ESR1ESR2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875775-B2 | Triphenylalkene derivatives and their use as selective estrogen receptor modulators | HORMOS MEDICAL OY LTD (FI) | 2005-04-05 | — | — | US | disclosed |