⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295825 | 0.75 | CHRM5 (0.30) | — | |
| SCHEMBL1830719 | 0.75 | CHRM5 (0.30) | — | |
| SCHEMBL308763 | 0.75 | — | — | |
| SCHEMBL13735001 | 0.75 | CHRM5 (0.31) | — | |
| SCHEMBL19096064 | 0.75 | — | — | |
| SCHEMBL308452 | 0.75 | — | — | |
| SCHEMBL8961813 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL377442 | 0.73 | HPGD (0.30) | — | |
| SCHEMBL25167863 | 0.72 | SIGMAR1 (0.30) | — | |
| SCHEMBL18706549 | 0.72 | SIGMAR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093239-B2 | Imidazopyridine kinase inhibitors | GLAXOSMITHKLINE LLC (US) | 2012-01-10 | — | — | US | disclosed |
| EP-2125748-B1 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | ASTRAZENECA AB (SE) | 2011-05-25 | — | — | EP | disclosed |