Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295825 | 1.00 | CHRM5 (0.30) | CHRM5CHRM3 | |
| SCHEMBL2392905 | 0.83 | SIGMAR1 (0.30) | — | |
| SCHEMBL25167863 | 0.83 | SIGMAR1 (0.30) | — | |
| SCHEMBL18706549 | 0.83 | SIGMAR1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL19947903 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL19947901 | 0.79 | — | — | |
| SCHEMBL25181136 | 0.78 | GNAI3 (0.33) | — | |
| SCHEMBL14675613 | 0.77 | GNAI3 (0.35) | — | |
| SCHEMBL63801 | 0.75 | — | — | |
| SCHEMBL19096064 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318408-A2 | TRI-CYCLIC PYRAZOLOPYRIDINE KINASE INHIBITORS | Vertex Pharmaceuticals Incorporated (US) | 2011-05-11 | — | — | EP | disclosed |