Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 14/20 | 0.53 |
| ▸ | MAOB | P27338 | 14/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072984 | 0.84 | GSK3B (0.81) | GSK3BMAOAMAOBPRKD3PRKCG | |
| SCHEMBL6380626 | 0.83 | MAOA (0.69) | GSK3BMAOAMAOBPRKD3PRKCG | |
| SCHEMBL6425435 | 0.83 | MAOA (0.62) | GSK3BMAOAMAOBPRKD3PRKCG | |
| SCHEMBL6380199 | 0.83 | MAOA (0.76) | GSK3BMAOAMAOBNSD2KDM4E | |
| SCHEMBL11072864 | 0.82 | GSK3B (0.80) | GSK3BMAOAMAOBPRKD3PRKCG | |
| SCHEMBL6385103 | 0.81 | MAOA (0.58) | GSK3BMAOAMAOBPRKD3PRKCG | |
| SCHEMBL6381820 | 0.81 | MAOA (0.68) | GSK3BMAOAMAOBNSD2RAD52 | |
| SCHEMBL3856314 | 0.80 | MAOA (0.70) | GSK3BMAOAMAOBPRKD3PRKCG | |
| SCHEMBL6380545 | 0.75 | MAOA (0.65) | GSK3BMAOAMAOBPRKD3PRKCG | |
| SCHEMBL4348852 | 0.74 | GSK3B (0.55) | GSK3BMAOAMAOBPRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907363-A4 | 8-AMINOQUINOLINES | UNIV MISSISSIPPI (US) | 2005-04-06 | — | — | EP | claimed |
| EP-0907363-A1 | 8-AMINOQUINOLINES | THE UNIVERSITY OF MISSISSIPPI (US) | 1999-04-14 | — | — | EP | claimed |
| WO-1997036590-A1 | 8-AMINOQUINOLINES | THE UNIVERSITY OF MISSISSIPPI (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0907363-A4 | 8-AMINOQUINOLINES | UNIV MISSISSIPPI (US) | 2005-04-06 | — | — | EP | disclosed |
| EP-0907363-A1 | 8-AMINOQUINOLINES | THE UNIVERSITY OF MISSISSIPPI (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997036590-A1 | 8-AMINOQUINOLINES | THE UNIVERSITY OF MISSISSIPPI (US) | 1997-10-09 | — | — | WO | disclosed |