Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimebutic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimebutic Acid SCHEMBL47533 | 0.83 | — | — | |
| Propylene Glycol SCHEMBL9720403 | 0.81 | ACACB (0.44) | TDP1ACACBACACATSHRACLY | |
| Pivalate SCHEMBL28654352 | 0.80 | TDP1 (0.56) | TDP1ACACBACACATSHROR51E2 | |
| Pivalate SCHEMBL27791440 | 0.80 | TDP1 (0.56) | TDP1ACACBACACATSHROR51E2 | |
| Dimebutic Acid SCHEMBL25275531 | 0.80 | — | — | |
| Dimebutic Acid SCHEMBL1176300 | 0.80 | — | — | |
| Dimebutic Acid SCHEMBL1962006 | 0.80 | — | — | |
| Dimebutic Acid SCHEMBL20139427 | 0.80 | — | — | |
| Dimebutic Acid SCHEMBL8383027 | 0.80 | — | — | |
| Dimebutic Acid SCHEMBL1055427 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050042536-A1 | Photosensitive resin composition comprising quinonediazide sulfate ester compound | DONGJIN SEMICHEM CO. LTD. (KR) | 2005-02-24 | — | — | US | disclosed |
| WO-2003036388-A1 | PHOTOSNESITIVE RESIN COMPOSITION COMPRISING QUINONEDIAZIDE SULFATE ESTER COMPOUND | DONGJIN SEMICHEM CO., LTD. (KR) | 2003-05-01 | — | — | WO | disclosed |