Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638408 | 1.00 | EPHX1 (0.56) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| Hydrochloric Acid SCHEMBL5385721 | 0.98 | EPHX1 (0.54) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| SCHEMBL10564045 | 0.80 | LOXL2 (0.44) | KDM4ELMNAMAPK1TAAR1MAOA | |
| Hydrochloric Acid SCHEMBL5378431 | 0.78 | LOXL2 (0.43) | KDM4ELMNAMAPK1TAAR1MAOA | |
| SCHEMBL7953179 | 0.78 | ANPEP (0.47) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| SCHEMBL5113171 | 0.78 | ESR1 (0.58) | SLC6A2TAAR1SLC7A5 | |
| SCHEMBL6533959 | 0.78 | ALPI (0.53) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| SCHEMBL11620748 | 0.78 | KDM4E (0.56) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| SCHEMBL10253191 | 0.77 | SLC6A2 (0.58) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| SCHEMBL5675489 | 0.77 | KDM4E (0.66) | EPHX1KDM4ELMNAMAPK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897058-B2 | Method for the preparation of enantiomerically enriched amines | DSM IP ASSETS B.V. (NL) | 2005-05-24 | — | — | US | disclosed |
| US-20040014181-A1 | Method for the preparation of enantiomerically enriched amines | DSM IP ASSETS B.V. (NL) | 2004-01-22 | — | — | US | disclosed |
| EP-1315827-A1 | METHOD FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED AMINES | DSM N.V. (NL) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002020820-A1 | METHOD FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED AMINES | DSM N.V. (NL) | 2002-03-14 | — | — | WO | disclosed |